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1

Pharmacology of cytarabine given as a continuous infusion followed by mitoxantrone with and without amsacrine/etoposide as reinduction chemotherapy for relapsed or refractory pediatric acute myeloid leukemia

Fevzi Ozkaynak, M., Avramis, Vassilios I., Carcich, Sherri, Ortega, Jorge A.

Journal:

Medical and Pediatric Oncology

Year:

1998

Language:

english

File:

PDF, 102 KB

english, 1998

2

Antibody formation during intravenous and intramuscular therapy with Erwinia asparaginase

Birgitte Klug Albertsen, Henrik Schrøder, Preben Jakobsen, Vassilios I. Avramis, Hans-Joachim Müller, Kjeld Schmiegelow, Niels T. Carlsen

Journal:

Pediatric Blood & Cancer

Year:

2002

Language:

english

File:

PDF, 91 KB

english, 2002

3

Comparison of intramuscular therapy with Erwinia asparaginase and asparaginase Medac: pharmacokinetics, pharmacodynamics, formation of antibodies and influence on the coagulation system

Birgitte Klug Albertsen, Henrik Schrøder, Jørgen Ingerslev, Preben Jakobsen, Vassilios I. Avramis, Hans-Joachim Müller, Niels T. Carlsen, Kjeld Schmiegelow

Journal:

British Journal of Haematology

Year:

2001

Language:

english

File:

PDF, 192 KB

english, 2001

4

Toxicity and efficacy of intensive chemotherapy for children with acute lymphoblastic leukemia (ALL) after first bone marrow or extramedullary relapse

Blythe Thomson, Julie R. Park, Judy Felgenhauer, Soheil Meshinchi, John Holcenberg, J. Russell Geyer, Vassilios Avramis, James G. Douglas, Michael R. Loken, Douglas S. Hawkins

Journal:

Pediatric Blood & Cancer

Year:

2004

Language:

english

File:

PDF, 117 KB

english, 2004

5

Biochemical pharmacology of 5,6-dihydro-5-azacytidine (DHAC) and DNA hypomethylation in tumor (L1210)-bearing mice

William C. Powell, Vassilios I. Avramis

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1988

Language:

english

File:

PDF, 487 KB

english, 1988

6

Pharmacodynamic and DNA methylation studies of high-dose 1-β-d-arabinofuranosyl cytosine before and after in vivo 5-azacytidine treatment in pediatric patients with refractory acute lymphocytic leukemia

Vassilios I. Avramis, Robert A. Mecum, Jonathan Nyce, David A. Steele, John S. Holcenberg

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1989

Language:

english

File:

PDF, 834 KB

english, 1989

7

Cellular metabolism of 5,6-dihydro-5-azacytidine and its incorporation into DNA and RNA of human lymphoid cells CEM/O and CEM/dCk(-)

Vassilios I. Avramis, William C. Powell, Robert A. Mecum

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1989

Language:

english

File:

PDF, 660 KB

english, 1989

8

Cellular metabolism of 1-β-d-arabinofuranosyl-5-azacytosine and incorporation into DNA and RNA of human lymphoid CEM/0 and CEM/dCk(−) cells

Vassilios I. Avramis, William C. Powell, Robert A. Mecum

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1989

Language:

english

File:

PDF, 631 KB

english, 1989

9

Anti-Erwiniaasparaginase antibodies during treatment of childhood acute lymphoblastic leukemia and their relationship to outcome: a case-control study

Birgitte Klug Albertsen, Kjeld Schmiegelow, Henrik Schrøder, Niels T. Carlsen, Steen Rosthøj, Vassilios I. Avramis, Preben Jakobsen

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2002

Language:

english

File:

PDF, 76 KB

english, 2002

10

In vitro and in vivo evaluations of the tyrosine kinase inhibitor NSC

Ioannis A. Avramis, Garyfallia Christodoulopoulos, Atsushi Suzuki, Walter E. Laug, Ignacio Gonzalez-Gomez, George McNamara, Edward A. Sausville, Vassilios I. Avramis

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2002

Language:

english

File:

PDF, 1.76 MB

english, 2002

11

Pharmacokinetic studies of 13-cis-retinoic acid in pediatric patients with neuroblastoma following bone marrow transplantation

A. A. Khan, Judith G. Villablanca, C. Patrick Reynolds, Vassilios I. Avramis

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1996

Language:

english

File:

PDF, 344 KB

english, 1996

12

Reversal of cytosine arabinoside (ara-C) resistance by the synergistic combination of 6-thioguanine plus ara-C plus PEG-asparaginase (TGAP) in human leukemia lines lacking or expressing p53 protein

Cecilia H. Fu, Sagrario Martin-Aragon, Kenneth I. Weinberg, Veronica C. Ardi, Peter V. Danenberg, Vassilios I. Avramis

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2001

Language:

english

File:

PDF, 259 KB

english, 2001

13

Protein phosphatase 1α-mediated stimulation of apoptosis is associated with dephosphorylation of the retinoblastoma protein

Wang, Rui-Hong, Liu, Cathy W Y, Avramis, Vassilios I, Berndt, Norbert

Journal:

Year:

2001

Language:

english

File:

PDF, 453 KB

english, 2001

14

Synthesis and Testing of New Antileukemic Schiff Bases ofN-Hydroxy-N′- Aminoguanidine Against CCRF-CEM/0 Human Leukemia Cellsin Vitroand Synergism Studies with Cytarabine (Ara-C)

Phanesh B. Koneru, Eric J. Lien, Vassilios I. Avramis

Journal:

Pharmaceutical Research

Year:

1993

File:

PDF, 1.02 MB

1993

15

2-Fluoro-ATP: A toxic metabolite of 9-β-D-arabinosyl-2-fluoroadenine

Vassilios I. Avramis, William Plunkett

Journal:

Biochemical and Biophysical Research Communications

Year:

1983

Language:

english

File:

PDF, 478 KB

english, 1983

16

Diet-induced obesity alters vincristine pharmacokinetics in blood and tissues of mice

James W. Behan, Vassilios I. Avramis, Jason P. Yun, Stan G. Louie, Steven D. Mittelman

Journal:

Pharmacological Research

Year:

2010

Language:

english

File:

PDF, 399 KB

english, 2010

17

Pharmacokinetic/Pharmacodynamic Relationships of Asparaginase Formulations

Dr Vassilios I. Avramis, Eduard H. Panosyan

Journal:

Clinical Pharmacokinetics

Year:

2005

Language:

english

File:

PDF, 358 KB

english, 2005

18

Intracellular pharmacodynamic studies of the synergistic combination of 6-mercaptopurine and cytosine arabinoside in human leukemia cell lines

Lilibeth V. Ramilo-Torno, Vassilios I. Avramis

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1995

Language:

english

File:

PDF, 1.01 MB

english, 1995

19

Preclinical pharmacology of the antitumor agentO-6-methylguanine in CDF1 mice

Vassilios I. Avramis, Kenneth K. Chan…

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1993

Language:

english

File:

PDF, 715 KB

english, 1993

20

Acute Lymphoblastic Leukaemia

Ettinger, Lawrence J., Ettinger, Alice G., Avramis, Vassilios I., Gaynon, Paul S.

Journal:

Year:

1997

Language:

english

File:

PDF, 1.70 MB

english, 1997

21

Antileukemic Activity Studies and Cellular Pharmacology of the Analogues of 2-Hydroxy-1H-Isoindole-1,3-Dione (Hisd) Alone and in Combination with Cytosine Arabinoside (ara-C) Against Human Leukemia Cells Cem/O

Nandy, Partha, Lien, Eric J., Avramis, Vassilios I.

Journal:

Acta Oncologica

Year:

1994

Language:

english

File:

PDF, 795 KB

english, 1994

22

Pharmacodynamics and Proposed Mechanism of Therapeutic Action and Host Toxicity of 9-β-D-Arabinofuranosyl-2-Fluoroadenine Monophosphate (F-araAMP) in P388 Murine Leukemia-Bearing Mice

Avramis, Vassilios I.

Journal:

Cancer Investigation

Year:

1989

Language:

english

File:

PDF, 666 KB

english, 1989

23

Synergistic Combinations of Nucleoside Analog Drugs with Other Drugs Induce Greater Apoptosis in Human Leukemic T-Cells

Nandy, Partha, Periclou, Antonia P., Avramis, Vassilios I.

Journal:

Nucleosides and Nucleotides

Year:

1997

Language:

english

File:

PDF, 357 KB

english, 1997

24

Glutaminase activity determines cytotoxicity of l-asparaginases on most leukemia cell lines

Parmentier, Jean Hugues, Maggi, Maristella, Tarasco, Erika, Scotti, Claudia, Avramis, Vassilios I., Mittelman, Steven D.

Journal:

Leukemia Research

Year:

2015

Language:

english

File:

PDF, 1.16 MB

english, 2015

25

Allergic reactions and antiasparaginase antibodies in children with high-risk acute lymphoblastic leukemia: A children's oncology group report

Ko, Richard H., Jones, Tamekia L., Radvinsky, David, Robison, Nathan, Gaynon, Paul S., Panosyan, Eduard H., Avramis, Ioannis A., Avramis, Vassilios I., Rubin, Joan, Ettinger, Lawrence J., Seibel, Nita

Journal:

Year:

2015

Language:

english

File:

PDF, 202 KB

english, 2015

26

Development of Zidovudine (AZT) Resistance in Jurkat T Cells Is Associated with Decreased Expression of the Thymidine Kinase (TK) Gene and Hypermethylation of the 5' End of Human TK Gene

Wu, Shijuan, Liu, Xiping, Solorzano, Michelle M., Kwock, Richard, Avramis, Vassilios I.

Journal:

Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology

Year:

1995

File:

PDF, 900 KB

1995

27

Development of Zidovudine (AZT) Resistance in Jurkat T Cells Is Associated with Decreased Expression of the Thymidine Kinase (TK) Gene and Hypermethylation of the 5' End of Human TK Gene

Wu, Shijuan, Liu, Xiping, Solorzano, Michelle M., Kwock, Richard, Avramis, Vassilios I.

Journal:

Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology

Year:

1995

File:

PDF, 900 KB

1995

28

Pharmacology of Combination Chemotherapy of Cytosine Arabinoside (Ara-C) and Uracil Arabinoside (Ara-U) or Tetrahydrouridine (THU) against Murine Leukemia L1210/0 in Tumor-Bearing Mice

Avramis, Vassilios I., Powell, William

Journal:

Cancer Investigation

Year:

1987

Language:

english

File:

PDF, 630 KB

english, 1987

29

Biochemical pharmacology of zidovudine in human T-lymphoblastoid cells (CEM)

Avramis, Vassilios I., Markson, Wendy, Jackson, Richard L., Gomperts, Edward

Journal:

Year:

1989

File:

PDF, 513 KB

1989

30

Comparative Toxicity by Sex Among Children Treated for Acute Lymphoblastic Leukemia: A Report From the Children's Oncology Group

Meeske, Kathleen A., Ji, Lingyun, Freyer, David R., Gaynon, Paul, Ruccione, Kathleen, Butturini, Anna, Avramis, Vassilios I., Siegel, Stuart, Matloub, Yousif, Seibel, Nita L., Sposto, Richard

Journal:

Pediatric Blood & Cancer

Year:

2015

Language:

english

File:

PDF, 182 KB

english, 2015

31

Biochemical pharmacology and DNA methylation studies of arabinosyl 5-azacytidine and 5,6-dihydro-5-azacytidine in two human leukemia cell lines PER-145 and PER-163

Kees, Ursula R, Avramis, Vassilios I

Journal:

Anti-Cancer Drugs

Year:

1995

File:

PDF, 543 KB

1995

32

Clinical Pharmacology of Asparaginases in the United States: Asparaginase Population Pharmacokinetic and Pharmacodynamic (PK-PD) Models (NONMEM) in Adult and Pediatric ALL Patients

Avramis, Vassilios I., Spence, Susan A.

Journal:

Journal of Pediatric Hematology/Oncology

Year:

2007

Language:

english

File:

PDF, 320 KB

english, 2007

33

Asparaginases

Avramis, Vassilios I.

Journal:

Journal of Pediatric Hematology/Oncology

Year:

2011

Language:

english

File:

PDF, 191 KB

english, 2011

34

Development of Resistance to Gamma Radiation in T-Lymphoblastic Cell Lines after Treatment with Chemotherapeutic Agents

Majlessipour, Fataneh, Kwock, Richard, Avramis, Vassilios

Journal:

Pediatric Research

Year:

1999

File:

PDF, 70 KB

1999

35

Effects of Lipopolysaccharide (LPS) and p38 MAP Kinase Pathway in Primary HIV-1 Infection of Normal Donor Peripheral Blood Mononuclear Cells (PBMC)

Arditi, Moshe, Equils, Ozlem, Solorzano, Michelle M, Avramis, Vassilios

Journal:

Pediatric Research

Year:

1999

File:

PDF, 70 KB

1999

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